3080 S. SR 157
Edwardsville,
IL
62025
The Comfort Inn® & Conference Center hotel in Edwardsville near Southern Illinois University will get you rested and ready for anything.
Our location off Interstate 270 in western Illinois makes it easy to explore a number of attractions with convenience at our Edwardsville hotel. Nearby attractions include:
The Lambert-St. Louis International Airport is a short drive away, so you can drop your bags off as soon as you land!